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WMCCU Department of Anesthesiology Publications, 2003-2004 Academic Year

(revised 09/21/04)

ABSTRACTS

Amar D, Zhang H, Heerdt PM (2003) Inflammatory markers and postoperative atrial fibrillation.  Anesthesiology 99:A200

Belmont MR, Lien CA, Tjan J, Patel S (2004) Pharmackokinetic profile of AV430A in human volunteers.  Can J Anesth 51:A69

Belmont MR, Lien CA, Tjan J, Patel S, Kopman A (2003) Dose-response relations of 430A under propofol, nitrous oxide, opioid anesthesia.  Anesthesiology 99:A1153

Belmont MR, Tjan J, Lien CA, Patel S (2004) Cardiovascular profile of AV430A in human volunteers.  Can J Anesth 51:A68

Brewer R, Herman M, Lien CA, Lubenow T, Silverstein JH, Yarmush J (2004) Comparison of the safety and efficacy of a patient-controlled transdermal fentanyl HC1 delivery system versus an intravenous morphine pump for the treatment of post-operative pain after major surgery: a randomized multicenter trail.  American Academy of Pain Medicine

Bullock SA, Platholi J, Hemmings HCJr, Tung HYL (2004) Differential regulation of protein phosphatase-1 complexes by neurabin-1. ASBMB, FASEB J 18:C163

Caiati J, Eliazo R, Lien CA, Fogarty-Mack P (2003) Timolol limits the increase in intraocular pressure during prone positioning for spine surgery.  J Neurosurg Anesth 15:A70

Caiati J, Eliazo R, Snow R, Lavyne M, Lien CA, Fogarty-Mack P (2003) Timolol reduces intra-ocular pressure (IOP) during prone positioning for spine surgery.  Anesthesiology 99:A309

Dingeman RS, Memtsoudis S, Heerdt PM (2003) Minimally invasive thoracic surgery: does it require less invasive monitoring?  Anesthesiology 99:A547

Dinner M (2003) Airway Problems in Neonates.  ASA Meeting, San Francisco, CA

Fontes ML, Mathew JP, Rinder H, Newman MF, Smith B, Rinder C and M. McSPI Research Group (2004) Cellular Inflammation During CPB: New Insight into Atrial Fibrillation. Anesth Analg 98:SCA134

Heerdt PM, Amar D, Zhang H, Park B, Flores R (2004) Minimally invasive resection does not alter the short-term inflammatory response to lobectomy.  Anesth Analg 98:SCA71

Heerdt PM, Markov NP (2003) Time dependence of halothane effects onleft ventricular contractility: evidence for anesthetic-induced myocardial remodeling.  Anesthesiology 99:A725

Hemmings HCJr, OuYang W (2003) Use-dependent block by isoflurane of presynaptic Na+ channels in rat neurohypophysial nerve terminals. Anesthesiology 99:A879
 
Hemmings HCJr, Westphalen RI (2003) Distinct effects of halothane, enflurane and isoflurane on basal glutamate versus GABA release. Anesthesiology 99:A881

Hemmings HCJr, Westphalen RI (2004) Selective effects of volatile ansthetics on basal and evoked glutamate and GABA release from isolated nerve terminals. 51th Annual Meeting of the AUA, Sacramento CA

Kjaer K, DiMaria LJ, Comerford M, Abramovitz SE, Swamidoss CP, Kiselev M, Gadalla F, Leighton BL (2003) Nausea and vomiting during elective cesarean sections: a comparison of oral sodium citrate and intravenous famotidine.  Anesthesiology 98:Supp 1:A35

Lien CA, Belmont MR, Tjan J, Patel S (2003) Pharmacodynamics of spontaneous and edrophonium-facilitated recovery following administration of 430A.  Anesthesiology 99:A1154

Milla F, Heerdt P, Skubas N, Girardi L, Lee L, Ko W, Tortolani A, Krieger K, Isom OW, Mack C (2004)  Epicardial beating heart cryoablation using a novel argon-based cryo-clamp.  4th Annual Conference on the Surgical Treatment of Atrial Fibrillation. San Antonio, TX

OuYang W, Hemmings HCJr (2003) Use-dependent block of Na+ channels in neurohypophysial nerve terminals by isoflurane, a volatile anesthetic. Soc Neurosci Abstr 29:579.3
 
OuYang W, Hemmings HCJr (2003) Effects of the volatile anesthetic isoflurane on Na+ tail currents in isolated neurohypophysial nerve terminals. Soc Neurosci Abstr 29:579.2

OuYang W, Wang G, Hemmings HCJr (2004) Distinct Rat neurohypophysial nerve terminal populations identified by size, electrophysiological properties and neuropeptide content. 37th Annual Winter Conference on Brain Research, Copper Mountain CO

Platholi J, Tung HYL, Hemmings HCJr (2004) Regulation of a protein phosphatase-1I complex in global cerebral ischemia. ASBMB, FASEB J 18:C304

Port JL, Yamaguchi K, Du B, De Lorenzo M, Chang M, Heerdt PM, Kopelovich L, Altorki NK, Subbaramaiah M, Dannenberg AJ (2004) Cytochrome P450 1B1 is induced by tobacco smoke in the aerodigestive tract.  Proceedings of the AACR

Pryor K, Whittaker M, Fahey TH III, Lien CA, Goldstein PA (2003) Perioperative elevation of inspired oxygen does not reduce surgical infection following laparotomy.  Anesthesiology 99:A93

Pryor K, Whittaker M, Fahey TH III, Lien CA, Goldstein PA (2003) Perioperative elevation of inspired oxygen does not reduce surgical infection following laparotomy.  Anesthesiology 99:A93

Samuels J (2004) Bariatric Anesthesia: A New Subspecialty. NYSSA Sphere

Skubas NJ (2003)  67-Year-Old Male with emphysema undergoes lung trasplantation. ASA Problem-Based Learning Discussions Meeting, San Fransisco, CA

Skubas NJ, Ryjikov N, Slepian R, Levin S, Girardi L, Krieger K, Tunick PA, Kronzon I (2004)  The effect of pericardiotomy on left ventricular diastolic myocardial tissue velocity.  15th Annual Scientific Sessions of the American Society of Echocardiography, PI-44

Swamidoss CP, Slepian RL, Lien CA (2003) Can we reliably select residents we would want to anesthetize us?  Anesthesiology 99:A1320

Swamidoss CP, Slepian RL, Lien CA (2003) Is there a gender gap in anesthesia resident education?  Anesthesiology 99:A1322

Topf N, Baron NL, Harrison NL (2003) A mutant GABAA receptor with normal GABA sensitivity but slective to different volatile anesthetics.  Anesthesiology 99:A882

Westphalen RI, Hemmings HCJr (2003) Selective depression by volatile anesthetics of glutamate and GABA release from isolated rat cortical nerve terminals. Soc Neurosci Abstr 29:902.7Yao FS, Ho CA (2003) Autologous normovolemic hemodilution decreases cerebral oxygen saturations in patients undergoing cardiac surgery.  Anesthesiology 99:A210

Yao FS, Ho CA (2004) The effects of blood transfusion on cerebral oxygen saturation.  Anesth Analg 98:SCA129

Ying S, Ferguson C, Homanics G, Goldstein PA (2003) Effects of isoflurane on thalamic neuronal excitability and synaptic transmission in GABAA-receptor a1 subunit double knock-in mice.  Soc Neurosci Abstr 29:571.1

CHAPTERS AND REVIEWS

Garwood S, Swamidoss CP, Davis EA, Sampson L, Hines RL (2003) A Case Series of Low Dose Fenoldopam in 70 Cardiac Surgical Patients at increased risk for Renal Dysfunction. “The Effect of Fenoldopam on renal dysfunction following cardiac surgery”.  J Cardiovasc Anesth 17:17-21

Harrison NL, Sear JW (2004) Intravenous anesthetics: Barbiturates, etomidate, propofol, ketamine and steriods. In Anesthetic Pharmacology, M Maze, AS Evers, eds (Churchill Livingstone, Philadelphia PA) pgs.395-416

Heerdt PM (2003) Cardiovascular adaptation to lung resection. In Thoracic Anesthesia, 3rd Edition, Kaplan JE, eds. (Churchill-Livingstone, New York, NY)

Heerdt PM, Malhotra J (2004) The right ventricular response to lung resection. Cardiovascular adaptation to lung resection. In Progress in Thoracic Anesthesia, Slinger PD, ed. (Lippincott Williams and Wilkins), pgs. 221-246

Hemmings HCJr (2004) Neuroprotection by Na+ channel blockade. J Neurosurg Anesthesiol 16:100-101

Hemmings HCJr, Girault JA (2004) Signal transduction mechanisms: receptor-effector coupling. In Anesthetic Pharmacology, M Maze, AS Evers, eds (Churchill Livingstone, Philadelphia PA) pgs.21-39

Malhotra V, Diwan S, Sudheendra V (2004) Anesthesia and the Renal and Genitourinary Systems.  In Anesthesia 6th Edition, Miller RD, ed. (Churchill-Livingstone, New York, NY)

Mussivand T, Heerdt PM, Margulies KB, Frazier OW, Singh G, Baba HA (2003) Mechanical circulatory devices in the treatment of heart failure.  In Pathophysiology of Cardiovascular Disease, Dhalla NS, Rupp H, Angel A, Pierce GN, eds. (Kluwer Academic Publishers) pgs. 619-631

Robicsek SA, Rogers R, Hemmings HCJr (2004) Pharmacotherapy in the neurosurgical intensive care unit. In Textbook of Neurointensive Care, AJ Layon, A Gabrielli, W Friedman, eds (Saunders, Philadelphia PA) pgs.649-681

Rosner H, Diwan S (2003) Gabapentin in Neuropathic Pain States.  In Advances in Pharmacologic Management of Pain: Current Understanding, Emerging Therapies, and Novel Approaches To Drug Discovery, Bountra, Munglani, Schmidts, eds. (Marcel Dekker Inc.) pgs. 781-794

Skubas N, Fontes M (2004)  Essentials of Pericardial Diseases.  The Greek E-Journal of Perioperative Medicine 2:25-33

Skubas N (2003)  Principles of Echocardiography for the Anesthesiologist. The Greek E-Journal of Perioperative Medicine 1:26-39

LETTERS, CASE REPORTS, AND CORRESPONDENCE

Lien CA (2004) What’s new in muscle relaxant development? The North Carolina Society of Anesthesiologists Newsletter 13:4-7

Mathew J, Fontes M, Mangano D  (2004) Letter to the Editor: Atrial fibrillation and risk of postoperative complication.  JAMA 29241-29242

Pryor K, Fahey III TH, Lien CA, Goldstein PA (2004)  Supplemental oxygen and risk of surgical site infection.  JAMA 291:1958-1959

Stein B, Fogarty Mack P (2003) Bronchospasm due to malpositioned esophageal temperature probe.  Anesth Analg 97:920-921

PAPERS

Barberi T, Klivenyi P, Calingasan NY, Lee H, Kawamata H, Loonam K, Perrier A, Bruses J, Rubio ME, Topf N, Tabar V, Harrison NL, Beal MF, Moore MAS, Studer L (2003) Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice.  Nature Biotechnology 21:1200-1207

Beilin Y, Zahn J, Abramovitz S, Bernstein HH, Hossain S, Bodian C (2003) Subarachnoid small-dose bupivacaine versus lidocaine for cervical cerclage.  Anesth Analg 97:56-61

Belmont MR, Lien CA, Tjan J, Bradley E, Stein B, Patel S, Savarese JJ (2004) Clinical pharmacology of GW280430A in humans.  Anesthesiology 100:768-773

Boros EE, Samano V, Ray JA, Thompson JB, Jung DK, Kaldor I, Koble CS, Martin MT, Styles VL, Mook RAJr, Feldman PL, Savarese JJ, Belmont MR, Bigham EC, Boswell GE, Hashim MA, Patal SS, Wisowaty JC, Bowers GD, Moseley CL, Walsh JS, Reese MJ, Rutkowske RD, Sefler AM, Spitzer TD (2003) Neuromuscular blocking activity and therapeutic potential of mixed-tetrahydoisoquinolinium halofumarates and halosuccinates in rhesus monkeys.  J Med Chem 46:2502-2515

Brown NI, Mack PF, Mitera DM, Dhar P (2003) Use of the proseal laryngeal mask airway in a pregnant patient with a difficult airway; a case study during electroconvulsive therapy.  Br J Anaesth 91:752-754

Castaldo P, Stefanoni P, Miceli F, Coppola G, Miraglia del Giudice E, Bellini G, Pascotto A, Trudell JR, Harrison NL, Annunziato L, Taglialatela M (2004) A novel hyperekplexia-causing mutation in the pre-TM1 segment of the human glycine receptor a1 subunit inhibits gating by agonists and impairs membrane expression. J Biol Chem, 279:25598-25604

Dhar P, Abramovitz S, DiMichele D, Gibb CB, Gadalla F (2003) Management of pregnancy in a patient with severe hemophilia A.  Br J Anaesth 91:432-435

Dhar P, Tedore T (2003) Awake Insertion of the Intubating Laryngeal Mask Airway using Dexmedetomidine Sedation. South African J Anaesth and Analg 9:9-10

Diwan S, Hemmings HCJr, Panchal S (2003) Symptomatic treatment of Chronic Back Pain: Determination of Optimal Signal Frequency and Preliminary Efficacy of a Targeted Non-Invasive Electronic Pain Control Device.  Anesth Analg 96:S1-S293

Fogarty-Mack P, Perrine K, Kobylarz E, Schwartz T, Lien CA (2004) Dexmedetomidine and neurocognitive testing in awake craniotomy.  J Neurosurg Anesth 16:20-25

Gurewitsch ED, Johnson E, Allen RH, Diament P, Fong J, Weinstein D, Chervenak FA (2003) The descent curve of the grandmultiparous woman.  Am J Obstet Gynecol  189:1036-1041

Hall AC, Rowan KC, Stevens RJN, Kelley JC, Harrison NL (2004) The effects of isoflurane on desensitized wild-type and 1(S270H) GABAA receptors.  Anesth Analg 98:1297-1304

Harrison NL (2003) Knockin’on the door of general anesthetic mechanisms ­ but will U.S. researchers be shut out?  Anesth Analg 97:616-618

Heerdt PM, Kang R, The A, Hashim M, Mook RJ, Savarese JJ (2004) Cardiopulmonary effects of the novel neuromuscular blocking drug GW280430A in dogs.  Anesthesiology 100:846-851

Ivascu Brown N, Fogarty Mack P, Mitera DM, Dhar P (2003) Use if the ProSeal laryngeal mask airway in a pregnant patient with a difficult airway.  Br J Anesth 91:752-754

Kash TL, Harrison NL (2003) Molecular volume determines the activity of the halogenated alkane bromoform at wild-type and mutant GABAA receptors.  Brain Res 960:36-41

Kash TL, Jenkins A, Kelley JC, Trudell JR, Harrison NL (2003) Coupling of agonist binding to channel gating in the GABAA receptor.  Nature 421:272-275

Kash TL, Trudell JR, Harrison NL (2004) Charged residues in the beta-2 subunit involved in GABA-A receptor activation.  J Biol Chem 279:4887-4893

Kash TL, Trudell JR, Harrison NL (2004) Structural elements involved in activation of the GABAA receptor. Trans Biochem Soc 32:540-546

Kjaer-Pedersen K, Comerford M, Gadalla F (2004) General anesthesia for cesarean delivery in a patient with paroxysmal nocturnal hemoglobinuria and thrombocytopenia.  Anesth Analg 98:1471-1472

Koyama MM, Heerdt PM, Levi R (2003) Increased severity of reperfusion arrhythmias in mouse hearts lacking histamine H3-receptors: evidence for a protective role of H3-receptors in myocardial ischemia.  Biochem Biophys Res Commun 4:792-796

Mathew JP, Fontes ML, Tudor JC, Ramsay J, Duke P, Mazer CD, Barash PG, Hsu P, Mangano DT (2004) A multicenter risk index for atrial fibrillation after cardiac surgery. JAMA 291:1720-1729

Naguib M, Lien CA, Aker J, Eliazo R (2004) Post-tentanic potentiation and fade in response to tetanic and train-of-four stimulation occur during succinylcholine-indeuced block.  Anesth Analg 1686-1691

Nishikawa K, Harrison NL (2003) The actions of sevoflurane and desflurane on the GABAA receptor: the effects of TM2 mutations in the a and b subunits.  Anesthesiology 99:678-684

OuYang W, Wang G, Hemmings HCJr (2003) Isoflurane and propofol inhibit presynaptic Na+ channels in isolated rat neurohypophysial nerve terminals. Mol Pharmacol 64:373-381

Perouansky M, Hemmings HCJr, Pearce RA (2004) Anesthetic effects on glutamatergic neurotransmission: lessons learned from a large synapse. Anesthesiology 100:470-472

Pryor K, Fahey III TH, Lien CA, Goldstein PA (2004) Surgical-site infection and the routine use of perioperative hyperoxia in a general surgical population.  JAMA 291:79-87

Rinder CS, Fontes M, Mathew JP, Rinder HM, Smith BR (2003) Neutrophil CD11b upregulation during cardiopulmonary bypass is associated with postoperative renal injury.  Ann Thorac Surg 75:899-905

Ruscito B, Harrison NL (2003) Hemoglobin metabolites mimic benzodiazepines - a mechanism for hepatic encephalopathy? Blood 102:1525-1528

Savarese JJ, Belmont MR, Hashim MA, Mook RAJr, Boros EE, Samano V, Patel SS, Feldman PL, Schultz J-A I, McNulty M, Spitzer T, Cohn DL, Morgan P, Wastila WB (2004) Preclinical pharmacology of GW280430A (AV430A) in the rhesus monkey and in the cat.  Anesthesiology 100:835-845

Schlame M, Kelley RI, Feigenbaum A, Towbin JA, Heerdt PM, Schieble T, Wanders RJ, DiMauro S, Blanck TJ (2003) Phospholipid adnormalities in children with Barth syndrome.  J Am Coll Cardiol 42:1994-1999

Schofield CM, Jenkins A, Harrison NL (2003) A highly conserved aspartic acid residue in the signature disulfide loop of the alpha-1 subunit is a determinant of gating in the glycine receptor.  J Biol Chem 278:34079-34083

Suzuki T, Lien CA, Belmont MR, Tjan J, Savarese JJ (2003) Edrophonium effectively antagonizes neuromuscular block at the laryngeal adductors induced by rapacuronium, rocuronium and cisatracurium, but not mivacurium.  Can J Anesth 50:879-885

Topf N, Jenkins A, Baron NV, Harrison NL (2003) The effects of isoflurane on GABAA receptors activated by full and partial agonists.  Anesthesiology 98:306-311




 

 

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