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Equilibrium [111In]J591 binding plot with LNCaP cells. The counts per minute (cpm) of specific bound [111In]J591 are plotted vs. the concentration of [111In]J591 added after subtracting the contribution of non specifically bound [111In]J591. Specific bound radiolabeled J591 (diamonds) and nonlinear regression curve fit (solid line) data are presented. Conducted as described in the Materials and Methods section |